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789
同济医院早前发现,有患者康复后再次感染病毒。
中国湖北省武汉市同济医院和广东省疾病预防控制中心先后发现,有患者治愈后病情反覆,引来民众担忧。
美国一名病毒学专家赵玉琪在接受境外媒体访问时解释,该批患者治愈后应产生抗体,他们并非再次感染,可能是核酸样本曾交叉感染,或他们仅是没有症状,并非完全清除病毒,故其后再次检测为确诊。
赵玉琪解释,要证实患者病情反覆,体内再次出现病毒,需了解患者最初检测为确诊,然后治愈,再使用同一类型的临床样本以相同的检测方法,确定为再次确诊。赵玉琪认为,若使用不同的诊断测试方法,都可能产生“实际阳性”和“虚假阳性”两种互相矛盾的结果。
赵玉琪强调,上述两间研究机构取样规模小,报告也没有提到这些病人是“康复”多长时间后再次检测的。专家强调,由于基于核酸的测定具有超级敏感性,样本的交叉感染也会导致“虚假阳性”的结果,若不是在专门的分子测试实验室里做检测,可能会出现交叉感染。
赵玉琪从病毒学分析指出,没有先例证明,在短时间内再次感染同一种病毒的情况,患者治愈后,会对同一病毒产生免疫反应,因此所谓“再感染”的可能性较低。
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