星期四 2025年 10月 09日
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【新冠肺炎】 港专家以仓鼠试验 染疫首七天是关键

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团队公布在研究中健康(左)及染疫(右)仓鼠的照片。

香港大学医学院微生物学系团队以仓鼠研究新冠病毒发现,感染首两至四日病情最严重,第七天就开始好转,而长者只要挨过这个转捩点便可顺利度过。

根据《星岛日报》报道,港大医学院微生物学系讲座教授袁国勇及研究团队,以三十七只金黄叙利亚仓鼠作研究对象,为全球首个有关动物的实验模型。

袁国勇指,团队为仓鼠注射病毒后,仓鼠第二日开始发病、第四日病情最严重会出现鼻黏膜、气管和肺部发炎及鼻黏膜脱落,可能更有肺出血。

“患者因为黏膜受损严重程度跟灼伤无异,会咳嗽得十分辛苦,但直至第七日,染病仓鼠开始好转,病毒量下降,抗体上升至第十四日仍然存在,估计长者只要度过第七天便一帆风顺。”

袁国勇估计,感染的长者只要度过第七天便一帆风顺。

他也提及,团队曾把康复仓鼠的血清注射入健康仓鼠,并再做病毒实验,发现获血清注射的仓鼠体内病毒量少九成,认为疫苗亦会有相同功效。

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“团队也把八只染病仓鼠分别放进八个有健康仓鼠的笼,模仿密切接触者环境,原健康仓鼠只有轻微病征,但病毒量跟染疫仓鼠一样,即病毒传播率达百分之百,传染能力极强。”

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袁国勇表示,病毒会入侵被注射病毒的仓鼠,但原健康仓鼠只有上呼吸道有病毒;他以戴口罩为例,患者戴口罩后释出的病毒量会较无戴口罩时少,而健康人士戴口罩后受感染的病毒量亦会较少。

“但若两人都没佩戴,健康人士吸取的病毒量会较高,反映的病征亦会较重。”

而他又建议,如果隔离设施不足,可将发病至第七日的年轻及健康患者转到二线隔离病床就医,甚至动用骏洋村及亚博馆等检疫地点。

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