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789
中国研究团队对重症患者的肺部进行活体病理分析,以寻找重症患者死亡主因。
中国医疗团队近日进行危重症确诊患者的肺部活体研究发现,患者肺部呈古铜色,出现大量肺部纤维化、细支气管壁坏死、右肺外层出血性坏死,或是导致患者出现严重呼吸衰竭,及重症患者死亡的主要原因。
据中国媒体报道,中科院院士王福生教授带领的医疗团队是于日前,进行危重症确诊患者的肺部活体研究,从组织中进行病理分析。
据报道,研究样本来自一名66岁患者,于1月4日从湖北武汉返回广东深圳,随后出现高烧和咳嗽症状,患有高血压。
患者的肺部组织在显微镜下的画面。
“他的胸部X光片检查显示,两肺部有多发阴影,并出现严重急性呼吸窘迫症候群(ARDS)、呼吸衰竭,随后医生为他进行肺部移植手术后,进行活体病理研究。”
研究结果显示,肺部出现弥漫性充血,多为点状出血和部分肺叶边缘坏死,支气管被粘液和出血渗出物覆盖;除肺部纤维化外,亦有部分透明变性,出血性梗死、小血管增生,血管壁增厚,管腔狭窄闭塞。惟未见有其他细菌、真菌感染。
研究团队认为,肺部组织在显微镜下,出现出血性坏死的位置是右肺外缘,可推测是重症患者的主要死亡原因和首先出现病变的原因,亦可解释患者为何有急性肺功能障碍。
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