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789
锺南山认为,由于无发烧患者比例高,可能出现漏诊。
中国卫健委高级别专家组组长、中国工程院院士锺南山领导香港及内地多名专家,周五在国际权威医学期刊《新英伦医学杂志》发表研究论文指出,研究发现,新冠肺炎无出现发烧症状的患者比例,较沙士和中东呼吸综合症(MERS)患者多,相关致死率1.4%,亦沙士及MERS低。研究团队认为,若确诊定义侧重于检测发烧,可能会出现漏诊。
由锺南山领衔的研究论文有37名作者,其中包括香港中文大学医学院内科及药物治疗学系系主任许树昌、广州南方医科大学、武汉市金银潭医院等研究人员。报告分析内地30个省份超过1000名新冠病毒确诊患者资料,收集时间截至上月29日,包括926宗非重症病例及173宗重症病例。
研究发现,患者年龄中位数为47岁,超过约60%患者为男性,死亡率为1.4%,潜伏期介乎2至7日,中位数4日,最长可达24日。研究指,检测确诊病例时,不能过于侧重患者是否发烧,约43.8%患者在入院时有发烧的情况;出现咳嗽的有67.8%。而肚泻并不常见,只有3.8%。另有88.7%住院期间发烧,不发烧的患者比例高于沙士的1%和中东呼吸综合症的2%。
研究数据显示,56.4%患者入院时的肺部CT显示有磨玻璃样斑块(ground-glass opacity)和51.8%的双肺斑片状影,另有逾20%无影像学和CT扫描异常。亦有17.9%患者是放射诊断下完全没有异常情况,超过80%入院病人出现淋巴细胞减少的情况。
在传播途径方面,除了飞沫传播和直接接触两种途径,目前亦有研究发现在胃肠道、唾液和尿液内检出病毒,可能存在其他潜在传播途径。
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