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中国郑州中铝物流中部陆港公司一列运输铝矿石的火车，周三晚上10时左右在河南巩义的该公司专用铁路避难线后脱轨翻侧压毁一民屋，造成多人失踪。至周五清晨5时49分，剩下2名失踪者的遗体已被寻获，加上之前4名遇难者，事故共造成6人死亡。

事发后，郑州市及巩义市等多部门组成工作组，派出逾200人到场展开抢救工作，同时调来2部分别100吨及150吨的吊车参与救援。

脱轨翻侧的货运火车共有25节，整列重约2350吨，其中车头及前13节车厢撞上民宅后，车厢交叠，且有大量铝矿石将房屋压毁。